E-mail:xiao_fei@fudan.edu.cn
Research direction:Periphery-braincrosstalk in the regulation of metabolic homeostasis
Education Background:
2007-2012 Institute for Nutritional Science, Chinese Academy of Sciences,PhD
2003-2007 Nan Chang University,Biotechnology,Bachelor
Professional Experience:
2022-presentInstitute for Translational Brain Research, Fudan University, Junior PrincipalInvestigator
2014-2021 Shanghai Institute of Nutrition and Health,Chinese Academy of Sciences,Associate Professor
2012-2014Institute for Nutritional Science, Chinese Academy of Sciences,Post-doctor
Awards:
2018 Shanghai Rising-Star Program
2016 The Third-class Prize for Shanghai Natural Science and Technology Award (Rank Third)
2016 Youth Innovation Promotion Association,Chinese Academy of Sciences
2016 Sanofifi-Aventis-ShanghaiInstitutes for Biological Sciences (SA-SIBS) scholarship program
2013 Sanofifi-Aventis-ShanghaiInstitutes for Biological Sciences (SA-SIBS) scholarship program
2012 Excellent Graduates in Shanghai
Grants:
NSFC General Program
NSFC Youth Foundation
China Postdoctoral Science Foundation Special Fund
China Postdoctoral Science Foundation General Fund
Chinese Academy of Sciences-funded Project
Publications：
1.Fei Xiao#, Haizhou Jiang#, Zi Li, Xiaoxue Jiang, Shanghai Chen, Yuguo Niu,Hanrui Yin, Yousheng Shu, Bo Peng, Wei Lu, Xiaoying Li, Zhigang Li, Shujue Lan, Xiaoyan Xu,Feifan Guo*(2023). Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice,Nature Communications,14:2523, DOI：10.1038/s41467-023-38141-0.
https://www.nature.com/articles/s41467-023-38141-0
2.Fei Xiao#,Jiali Deng#, Fuxin Jiao, Xiaoming Hu, Haizhou Jiang, Feixiang Yuan, Shanghai Chen, Yuguo Niu, Xiaoxue Jiang, Feifan Guo* (2022). Hepatic cytokine-inducible SH2-containing protein (CISH) regulates gluconeogenesis via cAMP-responsive element binding protein (CREB).FASEB J.2022 Oct;36(10):e22541.
https://pubmed.ncbi.nlm.nih.gov/36083102/
3. Fei Xiao, Feifan Guo* (2021). Impacts of essential amino acids on energy balance,Molecular Metabolism, Nov 14;101393.
https://www.sciencedirect.com/science/article/pii/S2212877821002489?via%3Dihub
4.Jiali Deng, Yajie Guo, Feixiang Yuan, Shanghai Chen, Hanrui Yin, Xiaoxue Jiang, Fuxin Jiao, Fenfen Wang, Hongbin Ji, Guohong Hu, Hao Ying, Yan Chen, Qiwei Zhai,Fei Xiao*, Feifan Guo* (2020). Autophagy inhibition prevents glucocorticoid-increased adiposity via suppressing BAT whitening,Autophagy, 16(3):451-465.
https://www.tandfonline.com/doi/full/10.1080/15548627.2019.1628537
5.Fei Xiao#, Yajie Guo#,Jiali Deng,Feixiang Yuan,Yuzhong Xiao,Lijian Hui,Yu Li,Zhimin Hu,Yuncai Zhou,Kai Li,Xiao Han,Qichen Fang,Weiping Jia,Yan Chen,Hao Ying,Qiwei Zhai,Shanghai Chen,Feifan Guo* (2019). Hepatic c-Jun regulates glucose metabolism via FGF21 and modulates body temperature through the neural signals,Molecular Metabolism, 20:138-148.
https://www.sciencedirect.com/science/article/pii/S2212877818309761?via%3Dihub
6. Fei Xiao#,Jiali Deng#,Yajie Guo,Yuguo Niu,Feixiang Yuan,Junjie Yu,Shanghai Chen,Feifan Guo* (2016). BTG1 ameliorates liver steatosis by decreasing stearoyl-CoA desaturase 1 (SCD1) abundance and altering hepatic lipid metabolism,Science Signaling, 9(428): ra50.
https://www.science.org/doi/10.1126/scisignal.aad8581?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
7. Fei Xiao,Jiali Deng,Junjie Yu,Yajie Guo,Shanghai Chen,Feifan Guo* (2016). A novel function of B-cell translocation gene 1 (BTG1) in the regulation of hepatic insulin sensitivity in mice via c-Jun,FASEB Journal, 30(1):348-359.
https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.15-278689
8. Fei Xiao,Ying Du,Ziquan Lv,Shanghai Chen,Jianmin Zhu,Hongguang Sheng,Feifan Guo* (2016). Effects of essential amino acids on lipid metabolism in mice and humans,Journal of Molecular Endocrinology, 57(4):223-231.
https://jme.bioscientifica.com/view/journals/jme/57/4/223.xml
9.Fei Xiao#,Junjie Yu#,Bin Liu,Yajie Guo,Kai Li,Jiali Deng,Jin Zhang,Chunxia Wang,Shanghai Chen,Ying Du,Yingli Lu,Yuzhong Xiao,Zhou Zhang,Feifan Guo* (2014). A novel function of MicroRNA 130a-3p in hepatic insulin sensitivity and liver steatosis,Diabetes, 63(8): 2631-2642.
https://diabetesjournals.org/diabetes/article/63/8/2631/15652/A-Novel-Function-of-MicroRNA-130a-3p-in-Hepatic
10.Fei Xiao#,Tingting Xia#,Ziquan Lv#,Qian Zhang,Yuzhong Xiao,Junjie Yu,Hao Liu,Jiali Deng,Yajie Guo,Chunxia Wang,Kai Li,Bin Liu,Shanghai Chen,Feifan Guo* (2014). Central prolactin receptors (PRLRs) regulate hepatic insulin sensitivity in mice via signal transducer and activator of transcription 5 (STAT5) and the vagus nerve,Diabetologia,57(10): 2136-44.
https://link.springer.com/article/10.1007%2Fs00125-014-3336-3
11.Fei Xiao,Junjie Yu,Yajie Guo,Jiali Deng,Kai Li,Ying Du,Shanghai Chen,Jianmin Zhu*,Hongguang Sheng*,Feifan Guo* (2014). Effects of individual branched-chain amino acids deprivation on insulin sensitivity and glucose metabolism in mice,Metabolism-Clinical and Experimental, 63(6):841-50.
https://linkinghub.elsevier.com/retrieve/pii/S0026-0495(14)00085-7
12.Junjie Yu#,Fei Xiao#,Qian Zhang,Bin Liu,Yajie Guo,Ziquan Lv,Tingting Xia,Shanghai Chen,Kai Li,Ying Du,Feifan Guo* (2013). PRLR regulates hepatic insulin sensitivity in mice via STAT5,Diabetes, 62(9): 3103-3113.
https://diabetesjournals.org/diabetes/article/62/9/3103/33976/PRLR-Regulates-Hepatic-Insulin-Sensitivity-in-Mice
13.Fei Xiao,Zhiying Huang,Houkai Li,Junjie Yu,Chunxia Wang,Shanghai Chen,Qingshu Meng,Ying Cheng,Xiang Gao,Jia Li,Yong Liu,Feifan Guo* (2011). Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways.Diabetes,60(3): 746-756.
https://diabetesjournals.org/diabetes/article/60/3/746/33536/Leucine-Deprivation-Increases-Hepatic-Insulin
Address:No.138, medical college road 
Postcode:200032 
Tel/Fax:021-54237056
Emial:itbr@fudan.edu.cn
