E-mail:xxjiang@fudan.edu.cn
Research direction: Mechanisms of metabolic diseases and neurological disorders
Education:
2015.9-2020.6 Shanghai Institute of Nutrition and Health, CAS, Physiology, Doctor
2011.9-2015.6 Henan Polytechnic University Biotechnology Bachelor
Work experience:
2020.7-2022.7 Shanghai Institute of Nutrition and Health, CAS, postdoctor
2023.1-until nowInstitute for Translational Brain Research,Fudan University,postdoctor
Publications:
1.Jiang X, Liu K, Jiang H, Yin H, Wang ED, Cheng H, Yuan F, Xiao F, Wang F, Lu W, Peng B, Shu Y, Li X, Chen S, Guo F. SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2. Cell Rep. 2023 Jan 31;42(1):111984.
https://doi.org/10.1016/j.celrep.2022.111984
2.Jiang X, Xiao F, Guo F. Oocyte TET3: an epigenetic modifier responsible for maternal inheritance of glucose intolerance. Signal Transduct Target Ther. 2022 Oct 8;7(1):357.
https://doi.org/10.1038/s41392-022-01170-0
3. Yin H, Yuan F, Jiao F, Niu Y,Jiang X, Deng J, Guo Y, Chen S, Zhai Q, Hu C, Li Y, Guo F. Intermittent Leucine Deprivation Produces Long-lasting Improvement in Insulin Sensitivity by Increasing Hepatic Gcn2 Expression. Diabetes. 2022 Feb 1;71(2):206-218.
https://doi.org/10.2337/db21-0336
3. Jiang X, Guo F. [The role and mechanism of amino acids in regulating hepatic glucose and lipid metabolism]. Sheng Li Xue Bao. 2021 Oct 25;73(5):723-733.
https://doi.org/10.13294/j.aps.2021.0064
4. Yuan F, Jiang H, Yin H,Jiang X, Jiao F, Chen S, Ying H, Chen Y, Zhai Q, Guo F. Activation of GCN2/ATF4 signals in amygdalar PKC-δ neurons promotes WAT browning under leucine deprivation. Nat Commun. 2020 Jun 5;11(1):2847.
https://doi.org/10.1038/s41467-020-16662-2
5. Deng J, Guo Y, Yuan F, Chen S, Yin H,Jiang X, Jiao F, Wang F, Ji H, Hu G, Ying H, Chen Y, Zhai Q, Xiao F, Guo F. Autophagy inhibition prevents glucocorticoid-increased adiposity via suppressing BAT whitening. Autophagy. 2020 Mar;16(3):451-465.
https://doi.org/10.1080/15548627.2019.1628537
6. Deng Y, Xiao Y, Yuan F, Liu Y,Jiang X, Deng J, Fejes-Toth G, Naray-Fejes-Toth A, Chen S, Chen Y, Ying H, Zhai Q, Shu Y, Guo F. SGK1/FOXO3 Signaling in Hypothalamic POMC Neurons Mediates Glucocorticoid-Increased Adiposity. Diabetes. 2018 Apr;67(4):569-580.
https://doi.org/10.2337/db17-1069