江海宙 博士后

日期:2022-02-15 点击数: 来源:


邮箱hzjiang@fudan.edu.cn

 

研究方向:   外周组织与中枢互作调控代谢稳态


经历简介:

教育经历:

2018.9-2023.6 中科院上海营养与健康研究所 病理学与病理生理学 医学博士(PhD.)

2014.9-2018.6 河南工业大学 生物技术 理学学士


工作经历:

2023.6-至今 复旦大学脑科学转化研究院 博士后


代表性论文:

(#第一作者)

1.Xiao F #, Jiang H #, Li Z, Jiang X, Chen S, Niu Y, et al. Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice.  Nat Commun 2023;14:2523.DOI: 10.1038/s41467-023-38141-0


2. Jiang X, Liu K,  Jiang H, Yin H, Wang ED, Cheng H, et al. SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2. Cell Rep. 2023;42:111984. DOI: 10.1016/j.celrep.2022.111984


3. Niu Y, Jiang H, Yin H, Wang F, Hu R, Hu X, et al. Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination. Diabetes 2022;71:921-933. DOI: 10.2337/db21-0857


4. Xiao F, Deng J, Jiao F, Hu X,  Jiang H, Yuan F, et al. Hepatic cytokine-inducible SH2-containing protein (CISH) regulates gluconeogenesis via cAMP-responsive element binding protein (CREB).  FASEB J 2022;36:e22541. DOI: 10.1096/fj.202200870R

 

5. Wang F, Xiao F, Du L, Niu Y, Yin H, Zhou Z, Jiang X, Jiang H, et al. Activation of GCN2 in macrophages promotes white adipose tissue browning and lipolysis under leucine deprivation. (2019) FASEB J 2021;35:e21652. DOI: 10.1096/fj.202100061RR

 

6. Yuan F, Yin H, Deng Y, Jiao F, Jiang H, Niu Y, et al. Overexpression of Smad7 in hypothalamic POMC neurons disrupts glucose balance by attenuating central insulin signaling. Mol Metab 2020;42:101084. DOI: 10.1016/j.molmet.2020.101084

 

7. Yuan F, Jiang H, Yin H, Jiang X, Jiao F, Chen S, et al. Activation of GCN2/ATF4 signals in amygdalar PKC-δ neurons promotes WAT browning under leucine deprivation. Nat Commun 2020;11:2847 DOI: 10.1038/s41467-020-16662-2

 

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