邮箱:zhang_ran@fudan.edu.cn
研究方向:离子通道门控机制和神经递质传递机制。
教育经历:
2013.08 – 2020.07 清华大学 博士 生物学
2009.09 – 2013.07 四川大学 学士 生物科学
工作经历:
2020.12 - 2022.12 清华大学 博士后 结构生物学
代表性论文:
1. Xiangyun Fang#, Haichao Jin#, Jin Wang*, Ran Zhang*, Baobin Li* (2025). Structural Insights into the Gating Mechanism of the Two-Pore Domain Potassium Channel THIK1. Nature Structural and Molecular Biology (Accepted)
2. Qixian He#, Ran Zhang#, Sandrine Tury#, Valérie Courgnaud, Fenglian Liu, Jean-luc Battini*, Baobin Li* & Qingfeng Chen* (2025). Structural basis of phosphate export by human XPR1. Nat Commun 16, 683 (2025). https://doi.org/10.1038/s41467-025-55995-8.
3. Ruizhu Chen#, Ran Zhang#, Lu Li#, Bozhan Wang#, Zhiwei Gao, Fenglian Liu, Yan Chen, Yutao Tian *, Baobin Li*, and Qingfeng Chen* (2024). Structure basis for sugar specificity of gustatory receptors in insects. Cell Discovery. https://doi.org/10.1038/s41421-024-00716-6.
4. Xu G#, Zhang R#, Li H, Yin K, Ma X, Lou Z*. (2022) Structural basis for the neurotropic AAV9 and the engineered AAV-PHP.eB recognition with cellular receptors. Molecular Therapy – Methods & Clinical Development, 26, 52–60.
5. Zhang R#, Xu G#, Cao L#, Sun Z#, He Y, Cui M, Sun Y, Li S, Li H, Qin L, Hu M, Yuan Z, Rao Z, Ding W, Rao Z, Lou Z*. (2019) Divergent engagements between adeno-associated viruses and their cellular receptor AAVR. Nature Communications, 10(1): 3760.
6. Zhang R#, Cao L#, Cui M#, Sun Z, Hu M, Zhang R, Stuart W, Zhao X, Yang Z, Li X, Sun Y, Li S, Li H, Ding W*, Lou Z*, Rao Z. (2019) Adeno-associated virus 2 bound to its cellular receptor AAVR. Nature Microbiology, 4(4): 675–682.
7. Cao L#, Zhang R#, Liu T#, Sun Z#, Hu M, Sun Y, Cheng L, Guo Y, Fu S, Hu J, Li X, Yu C, Wang H, Chen H, Li X, Fry EE, Stuart DI, Qian P*, Lou Z*, Rao Z. (2018) Seneca Valley virus attachment and uncoating mediated by its receptor anthrax toxin receptor 1. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 115(51): 13087–13092.
荣誉和奖励:
博士后创新人才支持计划(2021年)
清华大学“水木学者”(2020年)
清华大学优秀毕业生(2020年)
清华大学优秀博士学位论文(2020年)