邮箱：xiao_fei@fudan.edu.cn
研究方向: 外周组织与中枢互作调控代谢稳态的机制
经历简介：
教育经历：
2007-2012 中国科学院营养科学研究所，博士
2003-2007南昌大学，学士
工作经历：
2022-至今 复旦大学脑科学转化研究院，青年研究员/博士生导师
2014-2021中国科学院上海营养与健康研究所，副研究员
2012-2014 中国科学院营养科学研究所，博士后
荣誉和奖励：
入选上海市青年科技启明星计划
获上海市自然科学三等奖（排名第三）
入选中国科学院青年创新促进会会员
获上海高水平地方高校建设人才引进项目
获得赛诺菲·中科院上海生命科学研究院优秀青年人才奖励基金
获得赛诺菲·中科院上海生命科学研究院优秀博士后人才奖励基金
获得“上海市普通高等学校优秀毕业生”称号
主持项目：
国家自然科学基金委面上项目四项
国家自然科学基金委青年科学基金项目
中国博士后科学基金特别资助
中国博士后科学基金面上资助
中国科学院上海生命科学研究院博士后领域前沿项目
代表性论文：
1.Haizhou Jiang, Shihong Ni, Zi Li, Shanghai Chen, Xiaoying Li, Huijie Zhang, Wei L. Shen, Xiaoxue Jiang, Peixiang Luo, Yousheng Shu, Feixiang Yuan, Keixin Tong, Fei Xiao*, Feifan Guo* (2026). Leucine catabolic enzyme AUH regulates BAT thermogenesis via PPARγ HMGylation and RNA-binding function in male mice, Nature Communications, 17(1):5038.
https://www.nature.com/articles/s41467-026-71581-y
2. Haizhou Jiang, Feifan Guo*, Fei Xiao* (2025). Role of branched-chain amino acid catabolism in the regulation of adipocyte metabolism, Endocrinology, bqaf089. doi: 10.1210/endocr/bqaf089.
https://pubmed.ncbi.nlm.nih.gov/40338053/
3.Fei Xiao#, Haizhou Jiang#, Zi Li, Xiaoxue Jiang, Shanghai Chen, Yuguo Niu,Hanrui Yin, Yousheng Shu, Bo Peng, Wei Lu, Xiaoying Li, Zhigang Li, Shujue Lan, Xiaoyan Xu,Feifan Guo*(2023). Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice,Nature Communications,14:2523, DOI：10.1038/s41467-023-38141-0.
https://www.nature.com/articles/s41467-023-38141-0
4.Fei Xiao#,Jiali Deng#, Fuxin Jiao, Xiaoming Hu, Haizhou Jiang, Feixiang Yuan, Shanghai Chen, Yuguo Niu, Xiaoxue Jiang, Feifan Guo* (2022). Hepatic cytokine-inducible SH2-containing protein (CISH) regulates gluconeogenesis via cAMP-responsive element binding protein (CREB).FASEB J.2022 Oct;36(10):e22541.
https://pubmed.ncbi.nlm.nih.gov/36083102/
5.Fei Xiao, Feifan Guo* (2021). Impacts of essential amino acids on energy balance,Molecular Metabolism, Nov 14;101393.
https://www.sciencedirect.com/science/article/pii/S2212877821002489?via%3Dihub
6.Jiali Deng, Yajie Guo, Feixiang Yuan, Shanghai Chen, Hanrui Yin, Xiaoxue Jiang, Fuxin Jiao, Fenfen Wang, Hongbin Ji, Guohong Hu, Hao Ying, Yan Chen, Qiwei Zhai,Fei Xiao*, Feifan Guo* (2020). Autophagy inhibition prevents glucocorticoid-increased adiposity via suppressing BAT whitening,Autophagy, 16(3):451-465.
https://www.tandfonline.com/doi/full/10.1080/15548627.2019.1628537
7.Fei Xiao#, Yajie Guo#,Jiali Deng,Feixiang Yuan,Yuzhong Xiao,Lijian Hui,Yu Li,Zhimin Hu,Yuncai Zhou,Kai Li,Xiao Han,Qichen Fang,Weiping Jia,Yan Chen,Hao Ying,Qiwei Zhai,Shanghai Chen,Feifan Guo* (2019). Hepatic c-Jun regulates glucose metabolism via FGF21 and modulates body temperature through the neural signals,Molecular Metabolism, 20:138-148.
https://www.sciencedirect.com/science/article/pii/S2212877818309761?via%3Dihub
8.Fei Xiao#,Jiali Deng#,Yajie Guo,Yuguo Niu,Feixiang Yuan,Junjie Yu,Shanghai Chen,Feifan Guo* (2016). BTG1 ameliorates liver steatosis by decreasing stearoyl-CoA desaturase 1 (SCD1) abundance and altering hepatic lipid metabolism,Science Signaling, 9(428): ra50.
https://www.science.org/doi/10.1126/scisignal.aad8581?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
9.Fei Xiao,Jiali Deng,Junjie Yu,Yajie Guo,Shanghai Chen,Feifan Guo* (2016). A novel function of B-cell translocation gene 1 (BTG1) in the regulation of hepatic insulin sensitivity in mice via c-Jun,FASEB Journal, 30(1):348-359.
https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.15-278689
10.Fei Xiao,Ying Du,Ziquan Lv,Shanghai Chen,Jianmin Zhu,Hongguang Sheng,Feifan Guo* (2016). Effects of essential amino acids on lipid metabolism in mice and humans,Journal of Molecular Endocrinology, 57(4):223-231.
https://jme.bioscientifica.com/view/journals/jme/57/4/223.xml
11.Fei Xiao#,Junjie Yu#,Bin Liu,Yajie Guo,Kai Li,Jiali Deng,Jin Zhang,Chunxia Wang,Shanghai Chen,Ying Du,Yingli Lu,Yuzhong Xiao,Zhou Zhang,Feifan Guo* (2014). A novel function of MicroRNA 130a-3p in hepatic insulin sensitivity and liver steatosis,Diabetes, 63(8): 2631-2642.
https://diabetesjournals.org/diabetes/article/63/8/2631/15652/A-Novel-Function-of-MicroRNA-130a-3p-in-Hepatic
12.Fei Xiao#,Tingting Xia#,Ziquan Lv#,Qian Zhang,Yuzhong Xiao,Junjie Yu,Hao Liu,Jiali Deng,Yajie Guo,Chunxia Wang,Kai Li,Bin Liu,Shanghai Chen,Feifan Guo* (2014). Central prolactin receptors (PRLRs) regulate hepatic insulin sensitivity in mice via signal transducer and activator of transcription 5 (STAT5) and the vagus nerve,Diabetologia,57(10): 2136-44.
https://link.springer.com/article/10.1007%2Fs00125-014-3336-3
13.Fei Xiao,Junjie Yu,Yajie Guo,Jiali Deng,Kai Li,Ying Du,Shanghai Chen,Jianmin Zhu*,Hongguang Sheng*,Feifan Guo* (2014). Effects of individual branched-chain amino acids deprivation on insulin sensitivity and glucose metabolism in mice,Metabolism-Clinical and Experimental, 63(6):841-50.
https://linkinghub.elsevier.com/retrieve/pii/S0026-0495(14)00085-7
14.Junjie Yu#,Fei Xiao#,Qian Zhang,Bin Liu,Yajie Guo,Ziquan Lv,Tingting Xia,Shanghai Chen,Kai Li,Ying Du,Feifan Guo* (2013). PRLR regulates hepatic insulin sensitivity in mice via STAT5,Diabetes, 62(9): 3103-3113.
https://diabetesjournals.org/diabetes/article/62/9/3103/33976/PRLR-Regulates-Hepatic-Insulin-Sensitivity-in-Mice
15.Fei Xiao,Zhiying Huang,Houkai Li,Junjie Yu,Chunxia Wang,Shanghai Chen,Qingshu Meng,Ying Cheng,Xiang Gao,Jia Li,Yong Liu,Feifan Guo* (2011). Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways.Diabetes,60(3): 746-756.
https://diabetesjournals.org/diabetes/article/60/3/746/33536/Leucine-Deprivation-Increases-Hepatic-Insulin
地址：上海市徐汇区医学院路138号 
邮编：200032 
电话/传真：021-54237056 
邮箱：itbr@fudan.edu.cn 
