Email: wwxue@fudan.edu.cn
Research Direction:
1. Central nervous system regeneration
2. Organoids and spinal cord injury repair
Education:
2019/07-2021/09 Postdoc, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
2015/09-2019/06 Ph.D., Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Neurobiology
Publication
1. Weiwei Xue*, Huijuan Li, Jinhong Xu, Xiao Yu, Linlin Liu, Huihui Liu, Rui Zhao, Zhicheng Shao*. Effective cryopreservation of human brain tissue and neural organoids, Cell Reports Methods, 2024, 4, 100777.
2. Weiwei Xue#*, Bo Li#, Huihui Liu#, Yujie Xiao, Bo Li, Lei Ren, Huijuan Li, Zhicheng Shao*. Generation of Dorsoventral Human Spinal Cord Organoids via Functionalizing Composite Scaffold for Drug Testing. iScience, 2023, 26, 105898.
3. Weiwei Xue*, Jiacheng Du, Yunteng Li, Zhicheng Shao*. Protocol for cryopreserving neural organoids and human living brain tissue using MEDY. STAR Protocols, 2024, 5, 10346
4. Weiwei Xue#, Yannan Zhao#, Zhifeng Xiao, Xianming Wu, Dezun Ma et al. Epidermal growth factor receptor-extracellular-regulated kinase blockade upregulates TRIM32 signaling cascade and promotes neurogenesis after spinal cord injury, Stem Cells, 2020, 38(1): 118-133.
5. Weiwei Xue#, Haipeng Zhang#, Yongheng Fan, Zhifeng Xiao, Yannan Zhao et al. Upregulation of Apol8 by Epothilone D facilitates the neuronal relay of transplanted NSCs in spinal cord injury, Stem Cell Research & Therapy, 2021, 12(1): 300.
6. Weiwei Xue#, Caixia Fan#, Bing Chen, Yannan Zhao, Zhifeng Xiao et al. Direct neuronal differentiation of neural stem cells for spinal cord injury repair. Stem Cells, 2021, 1-8.
7. Weiwei Xue, Huannan Wang, Zhimeng Wang, Mengxi Qiu, Jing Che et al. Cloning and characterization of ifitm1 and ifitm3 expression during early zebrafish development. Zygote, 2016, 24:149-158.
8. Haipeng Zhang#, Weiwei Xue#, Xiaoyu Xue, Yongheng Fan, Yaming Yang et al. Spatiotemporal dynamic changes, proliferation, and differentiation characteristics of Sox9-positive cells after severe complete transection spinal cord injury. Experimental Neurology, 2021, 337:113556.
9. Wen Yin#, Weiwei Xue#, Hecheng Zhu, He Shen, Zhifeng Xiao et al. Scar tissue removal-activated endogenous neural stem cells aid Taxol-modified collagen scaffold to repair chronic long-distance transected spinal cord injury. Biomaterials Science, 2021, 9:4778-4792.
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