E-mail: xjguo20(AT)fudan
Research Area: Tumor-targeted therapy-related metabolism and endocytosis mechanisms
Brief Biography:
Education:
June 2020 – Present
Fudan University
M.D.-Ph.D. Program in Surgery
September 2015 – June 2020
Fudan University
B.M. in Clinical Medicine (Five-year Program)
Selected Publications:
l Guo X#, Huang X#, Yang X#, Lu J#, Wei C#, Gao C, Pei Y, Chen Y, Sun Q, Cai JB, Zhou J, Fan J, Ke AW, Shi Y*, Shen Y*, Zhang P*, Shi G*, Yang G*. Loss of 5-hydroxymethylcytosine induces chemotherapy resistance in hepatocellular carcinoma via the 5-hmC/PCAF/AKT axis. Cell Death Dis. 2023 Feb 2;14(2):79.
l Lu J#, Zhang P#, Huang X#, Guo X#, Gao C, Zeng H, Zheng Y, Wang S, Cai J, Sun Q, Shi Y, Zhou J, Ke A*, Shi G*, Fan J*. Amplification of spatially isolated adenosine pathway by tumor-macrophage interaction induces anti-PD1 resistance in hepatocellular carcinoma. J Hematol Oncol. 2021 Nov 27;14(1):200.
Guo X#, Lu J#, Zeng H#, Zhou R#, Sun Q#, Yang G, Pei Y, Meng X, Shen Y, Zhang P, Cai J, Huang P, Ke A, Shi Y, Zhou J, Fan J, Chen Y*, Yang L*, Shi G*, Huang X*. CTLA-4 Synergizes With PD1/PD-L1 in the Inhibitory Tumor Microenvironment of Intrahepatic Cholangiocarcinoma. Front Immunol. 2021 Aug 30;12:705378.