Zhixin Qiu’s laboratory is systematically studying the molecular mechanisms and therapeutic opportunaties during tumorigenesis and drug resistance, through integrating a series of wet-dry-lab techniques, including bioinformatics, single cell sequencing, CRISPR/Cas9 screening and tumor organoid culture.
Zhixin Qiu#, Linjie Zhao#, Jia Z Shen#, Zhengyu Liang, Qiulian Wu, Kailin Yang, Lihua Min, Ryan Gimple, Qiyuan Yang, Shruti Bhargava, Chunyu Jin, Cheryl Kim, Denise Hinz, Deobrat Dixit, Jean Bernatchez, Briana Prager, Guoxin Zhang, Zhen Dong, Deguan Lv, Xujun Wang, Leo Kim, Zhe Zhu, Katherine jones, Ye Zheng, Xiuxing Wang, Jair Siqueira-Neto, Lukas Chavez, Xiangdong Fu, Charles Spruck, and Jeremy Rich. Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells. Cancer Discovery 2021 online.
Jia Z Shen#, Zhixin Qiu#, Qiulian Wu, Darren Finlay, Guillermina Garcia, Dahui Sun, Juha Rantala, William Barshop, Jennifer L Hope, Ryan C Gimple, Olle Sangfelt, Linda M Bradley, James Wohlschlegel, Jeremy N Rich*, Charles Spruck*. FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells. Cell 2021; 184(2):352-369.e23.
Zhixin Qiu#, Hong Li#, Zhengtao Zhang#, Zhenfeng Zhu, Sheng He, Xujun Wang, Pengcheng Wang, Jianjie Qin, Liping Zhuang, Wei Wang, Fubo Xie, Ying Gu, Keke Zou, Chao Li, Chun Li, Chenhua Wang, Jin Cen, Xiaotao Chen, Yajing Shu, Zhao Zhang, Lulu Sun, Lihua Min, Yong Fu, Xiaowu Huang, Hui Lv, He Zhou, Yuan Ji, Zhigang Zhang, Zhiqiang Meng, Xiaolei Shi*, Haibin Zhang*, Yixue Li*, Lijian Hui*. A Pharmacogenomic Landscape in Human Liver Cancers. Cancer Cell 2019; 36(2):179-193.e11.
Zhixin Qiu#, Keke Zou#, Liping Zhuang#, Jianjie Qin#, Hong Li, Chao Li, Zhengtao Zhang, Xiaotao Chen, Jin Cen, Zhiqiang Meng*, Haibin Zhang*, Yixue Li*, Lijian Hui*. Hepatocellular carcinoma cell lines retain the genomic and transcriptomic landscapes of primary human cancers. Scientific Reports 2016; 27411.
Address: Floor 2, Building B, Medical Research Building, 131 Dong'an Road, Xuhui District, Shanghai
Postcode: 200032
Telephone/Fax: 021-54237056
Email: qiuzhixin@fudan.edu.cn