实验室通过内源信号光学成像、双光子钙信号成像、电生理、形态学、行为学、人工神经网络模型等技术手段,研究大脑皮层的功能结构和感知觉信息的处理机制。近期主要研究方向包括:
1.正常和疾病情况下的皮层功能结构
2.大脑皮层自发活动与介观功能连接
3.视觉信息的并行处理和整合机制
4.视皮层神经元的深度学习卷积神经网络模型
Roe AW*, Chelazzi L, Connor CE, Conway BR, Fujita I, Gallant J, Lu H, Vanduffel W (2012) Toward a unified theory of visual area V4. Neuron, 74(2):12-29. (Review)
Rasch MJ*, Chen M, Wu S, Lu HD, Roe AW. (2013) Quantitative inference of population response properties across eccentricity from motion-induced maps in macaque V1. J Neurophysiol. 109(5):1233-1249.
Li PC, Zhu SD, Chen M, Han C, Xu HR, Hu JM, Fang Y, Lu HD*. (2013) A motion direction preference map in monkey V4. Neuron 78: 376–388.
Chen M, Li P, Zhu S, Han C, Xu H, Fang Y, Hu J, Roe AW, Lu HD* (2016) An orientation map for motion boundaries in macaque V2. Cerebral Cortex, 26:279–287.
Liu L, She L, Chen M, Liu T, Lu HD, Dan Y, Poo M* (2016) Spatial structure of neuronal receptive field in awake monkey secondary visual cortex (V2). PNAS. 113:1913-1918.
Xu H, Han C, Chen M, Li P, Zhu S, Fang Y, Hu J, Ma H, Lu HD* (2016) Rivalry-like neural activity in primary visual cortex in anesthetized monkeys. The Journal of Neuroscience, 36(11): 3231-3242.
Lu HD*, Chen G, Cai J, Roe AW (2017) Intrinsic signal optical imaging of visual brain activity: Tracking of fast cortical dynamics. Neuroimage. 148:160-168.
Chen G*, Lu HD, Tanigawa H, Roe AW (2017) Solving visual correspondence between the two eyes via domain-based population encoding in nonhuman primates. PNAS. 114(49):13024-13029.
Hu J, Ma H, Zhu S, Li P, Xu H, Fang Y, Chen M, Han C, Fang C, Cai X, Yan K, Lu HD*. (2018) Visual Motion Processing in Macaque V2. Cell Reports 25(1), 157–167.
Fang Y, Chen M, Xu H, Li P, Han C, Hu J, Zhu S, Ma H, Lu HD* (2019) An orientation map for disparity-defined edges in area V4. Cerebral Cortex. 29(2):666-679.
Tang R, Song Q, Li Y, Zhang R, Cai X, Lu HD* (2020) Curvature-processing domains in primate V4. eLife. 9:e57502.
Ma H, Li P, Hu J, Cai X, Song Q, Lu HD* (2021) Processing of motion-boundary orientation in macaque V2. eLife. 10:e61317.
Fang C, Yan K, Liang C, Wang J, Cai X, Zhang R, Lu HD* (2022) Function-specific projections from V2 to V4 in macaques. Brain Structure and Function. 227(4), 1317–1330.
Fang C, Cai X, Lu HD* (2022) Orientation anisotropies in macaque visual areas. PNAS. 119(15)e2113407119.
Cai X, Xu H, Han C, Li P, Wang J, Zhang R, Tang R, Fang C, Yan K, Song Q, Liang C, Lu HD*. (2023) Mesoscale functional connectivity in macaque visual areas. Neuroimage. 271:120019.
地址: 上海市徐汇区东安路131号医学科研楼二楼
邮编: 200032
电话/传真: 021-54237056
邮箱: haidong@bnu.edu.cn