Johnson, N.R., Yuan, P., Castillo, E. et al. CSF1R inhibitors induce a sex-specific resilient microglial phenotype and functional rescue in a tauopathy mouse model. Nat Commun 14, 118 (2023). https://doi.org/10.1038/s41467-022-35753-w
PLD3 affects axonal spheroids and network defects in Alzheimer’s disease. Yuan P, Zhang MY, Tong L, Morse T, McDougal R, Hui, D, Chan D, Yifei C, Grutzendler J. Nature, https://www.nature.com/articles/s41586-022-05491-6
RecV recombinase system for spatiotemporally controlled light-inducible genomic modifications. Yao SY#, Yuan P#, Ouellette B, Zhou T, Mortrud M, Balaram P, Chatterjee S, Wang Y, Daigle TL, Tasic B, Kuang XL, Gong H, Luo QM, Zeng SQ, Curtright A, Dhaka A, Kahan A, Gradinaru V, Chrapkiewicz R, Schnitzer M, Zeng HK, Cetin AH. Nature Method, 17: 422-429, 2020
TREM2 haplodeficiency in mice and humans impairs the microglia barrier function leading to decreased amyloid compaction and severe axonal dystrophy. Yuan P, Condello C, Keene DC, Wang YM, Bird TD, Paul SM, Luo WJ, Colonna M, Baddeley D, Grutzendler J. Neuron 90: 724-739, 2016
Attenuation of β-amyloid deposition and neurotoxicity by chemogenetic modulation of neural activity. Yuan P, Grutzendler J. Journal of Neuroscience 36(2): 632-641, 2016
Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques. Condello C#, Yuan P#, Schain A, Grutzendler J. Nature communications 6: 6176, 2015
Regional Blood Flow in the Normal and Ischemic Brain Is Controlled by Arteriolar Smooth Muscle Cell Contractility and Not by Capillary Pericytes. Hill RA#, Tong L#, Yuan P#, Murikinati S, Gupta S, Grutzendler J. Neuron 87(1): 95-110, 2015